Senior Bioinformatics Scientist Job at Integrated Resources, Inc ( IRI ), Cambridge, MA

blI5VW05RDVJTWIyS09VVHVmcWV6ZzZzV1E9PQ==
  • Integrated Resources, Inc ( IRI )
  • Cambridge, MA

Job Description

Job Description:

Department: Data and Genome Sciences

Group: Precision Genetics

The Precision Genetics group within the Data and Genome Sciences Department is seeking a skilled Contractor to join our Computational Precision Immunology team. We are looking for a data scientist with extensive experience in multi-modal and multi-scale data analyses to contribute to our innovative research efforts.

Key Responsibilities:

  • Data Ingestion: Query external databases to acquire relevant multi-omics datasets (e.g., PubMed, Gene Expression Omnibus, ArrayExpress, gnomAD, GTEx, Ensembl).
  • RNA-seq Analysis: Perform quality control (QC) and analysis of bulk and single-cell RNA-seq data using state-of-the-art methods (e.g., FastQC, STAR, Limma, DESeq2, clusterProfiler, Seurat, scanpy, LeafCutter).
  • Multi-Omics Analysis: Analyze diverse molecular data types including spatial transcriptomics (e.g., Slide-seq, MERFISH, squidpy) and proteomics (e.g., OLINK, mass spectrometry-based approaches).
  • Data Integration: Integrate multi-omics datasets, including gene/protein expression, mRNA splicing, spatial transcriptomics, and genotype data.
  • Documentation: Prepare detailed documentation of analysis methods and results in a timely manner.

Required Qualifications:

  • Ph.D. in Computational Biology or a related field.
  • A proven track record of over 5 years in multi-omics analysis.
  • Fundamental understanding of statistical methods and multi-omics data analysis and integration (e.g., RNA-Seq, single-cell RNA-Seq, genotype, spatial transcriptomics, OLINK).
  • Proficiency in R, Python, and Bash, with the ability to establish best practices for reproducible data analyses.
  • Experience with high-performance computing (HPC) systems and AWS Cloud Computing (e.g., IAM, S3 buckets).
  • A collaborative and self-motivated individual with a strong work ethic, capable of managing multiple objectives in a dynamic environment and adapting to changing priorities.
  • Excellent written and verbal communication skills.

Preferred Qualifications:

  • Experience in processing and analyzing real-world data.
  • Familiarity with spatial transcriptomics analysis.
  • Knowledge of statistical and population genetics principles.

Key Skills:

  • Required expertise with multi-omics data analysis and integration (e.g., RNA-Seq, single-cell RNA-Seq.
  • Transcriptomics analysis.
  • Proficiency in R and Bash.
  • High-performance computing (HPC) systems and AWS Cloud Computing (e.g., IAM, S3 buckets).

Job Tags

For contractors,

Similar Jobs

24 Seven Talent

Report Specialist Job at 24 Seven Talent

 ...detail-oriented, supporting both brick-and-mortar stores and online sales channels. Role Overview: The Data Entry / Report Specialist will support retail operations, customer service, and reporting. This is a temporary-to-permanent position filling in for an... 

NEWARK COMMUNITY HEALTH CENTERS, INC.

Director of Nursing Job at NEWARK COMMUNITY HEALTH CENTERS, INC.

 ...to meeting the health care needs of the medically underserved in the greater Newark area. Join us as we expand! The Director of Nursing (DON) is responsible for the leadership and organization of the nursing team. The DON will also function as a Risk Manager for the... 

Talentoma

Remote Customer Support Specialist Job at Talentoma

Remote Customer Support Specialist (Work From Home) | $3,300$3,900/month Were hiring Remote Customer Support Specialists to join our growing team. This is a fully remote / work-from-home customer service role focused on handling inbound calls and helping customers...

SPECTRAFORCE

Senior Quality Assurance Associate Job at SPECTRAFORCE

 ...Job Title: Quality Assurance Senior Associate Duration: 12 Months Location: Holly Springs, NC 27540 Note : Fully Onsite, Shift Work Schedule (includes weekends, and possibly nights) Once shift is determined shifts will be on a stable schedule. Must have :... 

Diversicare Healthcare Services, LLC

Director of Nursing Job at Diversicare Healthcare Services, LLC

 ...Lead with Excellence as the Director of Nursing- RN at Diversicare of Amory in Amory, MS! Are you ready to take the helm of the nursing department and make a profound impact on the lives of patients and residents? Diversicare is seeking a passionate Director of Nursing...